Description

5''-S-[3-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Propyl]-2'',3''-o-(1-Methylethylidene)-5''-Thio-Adenosine is a sophisticated, high-purity nucleoside derivative designed for advanced chemical synthesis and pharmaceutical research. This compound serves as a critical building block in the development of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers requiring reliable, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and cancer.
• Antiviral Drug Research: Used in the development of prodrugs and modified nucleosides to enhance bioavailability and therapeutic efficacy.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Bioconjugation & Probe Development: The reactive phthalimide (isoindole-1,3-dione) moiety allows for selective conjugation in the creation of labeled probes or targeted drug delivery systems.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate nucleoside-metabolizing pathways.
• Fine Chemical Synthesis: Used in custom synthesis and contract manufacturing for specialized, high-value chemical entities.

Basic Information

Item	Information
Product Name	5''-S-[3-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Propyl]-2'',3''-o-(1-Methylethylidene)-5''-Thio-Adenosine
CAS No.	263715-50-0
Molecular Formula	C25H26N8O5S
Molecular Weight	550.59 g/mol
Synonyms	5'-S-[3-(1,3-Dioxoisoindolin-2-yl)propyl]-2',3'-O-isopropylidene-5'-thioadenosine; 2',3'-O-Isopropylidene-5'-S-[3-(phthalimido)propyl]-5'-thioadenosine; 5'-Deoxy-5'-[(3-phthalimidopropyl)thio]-2',3'-O-isopropylideneadenosine; N6-[(1R,2S,3R,4R)-2,3-O-Isopropylidene-4-[[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propyl]thio]cyclopentyl]adenine; Adenosine, 5'-S-[3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]-2',3'-O-(1-methylethylidene)-5'-thio-
EINECS	Contact for details

Quality Control

Our 5''-S-[3-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Propyl]-2'',3''-o-(1-Methylethylidene)-5''-Thio-Adenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The product is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at -20°C to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.