Description

4-(4-Chloro-Phenyl)-5-(4-Trifluoromethoxy-Phenyl)-4H-[1,2,4]Triazole-3-Thiol is a high-purity, specialized heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both chloro and trifluoromethoxy phenyl substituents on a triazole-thiol core, makes it an invaluable intermediate for developing novel active ingredients. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel therapeutic agents, particularly for developing molecules with potential anti-inflammatory, antiviral, or anticancer activity.
• Agrochemical Research: Serves as a core scaffold for designing and synthesizing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the triazole-thiol moiety.
• Material Science: Used in the development of advanced polymers, ligands for metal-organic frameworks (MOFs), and specialty chemicals requiring specific heterocyclic functionalities.
• Chemical Synthesis: Acts as a versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the exploration of new chemical spaces.

Basic Information

Product Name	4-(4-Chloro-Phenyl)-5-(4-Trifluoromethoxy-Phenyl)-4H-[1,2,4]Triazole-3-Thiol
CAS No.	263707-20-6
Molecular Formula	C15H9ClF3N3OS
Molecular Weight	371.76 g/mol
Synonyms	4-(4-Chlorophenyl)-5-[4-(trifluoromethoxy)phenyl]-4H-1,2,4-triazole-3-thiol; 4-(p-Chlorophenyl)-5-[p-(trifluoromethoxy)phenyl]-4H-1,2,4-triazole-3-thiol; 1,2,4-Triazole-3-thiol, 4-(4-chlorophenyl)-5-[4-(trifluoromethoxy)phenyl]-; 263707-20-6; 4H-1,2,4-Triazole-3-thiol, 4-(4-chlorophenyl)-5-[4-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our production of 4-(4-Chloro-Phenyl)-5-(4-Trifluoromethoxy-Phenyl)-4H-[1,2,4]Triazole-3-Thiol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supported by a detailed Certificate of Analysis (COA). We are committed to meeting the exacting standards required for research and development applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its property of being easily oxidized, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain product integrity. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.