Description

4-Methyl-2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole-5-Carbohydrazide is a high-value heterocyclic building block and intermediate characterized by its thiazole core and trifluoromethylphenyl substituent. This compound matters for its role in facilitating the synthesis of novel molecules with enhanced biological activity and physicochemical properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for drug discovery and the creation of advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for anti-infective, anti-inflammatory, or kinase inhibitor candidates.
• Agrochemical Research: Serves as a crucial building block for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Material Science Precursor: Used in the synthesis of specialized ligands, organic semiconductors, or liquid crystals where the trifluoromethyl group can modulate electronic properties.
• Chemical Biology Probe: Employed in medicinal chemistry to create molecular probes for studying enzyme function or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-Methyl-2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole-5-Carbohydrazide
CAS No.	263387-25-3
Molecular Formula	C12H10F3N3OS
Molecular Weight	301.29 g/mol
Synonyms	4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbohydrazide; 5-Hydrazinylcarbonyl-4-methyl-2-[4-(trifluoromethyl)phenyl]thiazole; 2-(4-Trifluoromethylphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid hydrazide; 4-Methyl-2-(4-trifluoromethylphenyl)thiazole-5-carbohydrazide; 1,3-Thiazole-5-carbohydrazide, 4-methyl-2-[4-(trifluoromethyl)phenyl]-; 263387-25-3
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole-5-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.