Description

3-Quinolinecarbonitrile, 4-(1H-Indazol-6-Ylamino)-6-Methoxy-7-[3-(4-Morpholinyl)Propoxy]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of targeted kinase inhibitors. It is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in the discovery of novel therapeutics for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: Primary use as a sophisticated building block in the multi-step synthesis of novel drug candidates, particularly kinase inhibitors.
• Oncology Research: Serves as a core scaffold in the development of targeted cancer therapies that modulate specific cellular signaling pathways.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Biochemical Assay Development: Employed as a reference standard or probe molecule in high-throughput screening and enzymatic assays.
• Preclinical Studies: Utilized in the synthesis of compounds for pharmacokinetic, pharmacodynamic, and toxicology evaluations.
• Custom Synthesis: A starting point for the contract manufacturing of specialized, non-commercial chemical entities for client-specific research programs.

Basic Information

Product Name	3-Quinolinecarbonitrile, 4-(1H-Indazol-6-Ylamino)-6-Methoxy-7-[3-(4-Morpholinyl)Propoxy]-
CAS No.	263170-58-7
Molecular Formula	C25H26N6O2
Molecular Weight	442.52 g/mol
Synonyms	4-(1H-Indazol-6-ylamino)-6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinoline-3-carbonitrile; 4-(1H-Indazol-6-ylamino)-6-methoxy-7-(3-morpholinopropoxy)quinoline-3-carbonitrile; 7-[3-(4-Morpholinyl)propoxy]-4-(1H-indazol-6-ylamino)-6-methoxy-3-quinolinecarbonitrile; Kinase Inhibitor Intermediate 263170-58-7; CAS 263170-58-7
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced pharmaceutical intermediates. Each batch is characterized and controlled using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, providing full transparency and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.