Description

S-2-(4-Nitrobenzyl)-Diethylenetriamine Penta-T-Butyl Acetate is a specialized, high-purity chemical intermediate featuring a protected amine and ester functional groups. This compound is critical for advanced organic synthesis, particularly in the development of pharmaceuticals and complex ligands where controlled reactivity and stereochemistry are paramount. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, catalyst design, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological and oncological pathways.
• Ligand Synthesis: Used in the preparation of sophisticated polydentate ligands for asymmetric catalysis and metal complexation studies.
• Peptidomimetic Research: Acts as a backbone or side-chain component in the design of peptide analogs and protease inhibitors.
• Chemical Biology Probes: Employed in the development of molecular probes and tags for studying enzyme function and protein interactions.
• Advanced Material Precursor: Potential use in creating functionalized polymers or dendrimers with specific chemical handles.

Basic Information

Product Name	S-2-(4-Nitrobenzyl)-Diethylenetriamine Penta-T-Butyl Acetate
CAS No.	262855-60-7
Molecular Formula	C31H53N5O8
Molecular Weight	623.79 g/mol
Synonyms	S-2-(4-Nitrobenzyl)-Diethylenetriamine Penta-tert-Butyl Acetate; Diethylenetriamine, N1-[2-[(4-nitrophenyl)methyl]-1-oxo-2-[(2,2,2-trichloroethoxy)carbonyl]ethyl]-, penta-1,1-dimethylethyl ester; (S)-2-(4-Nitrobenzyl)-N,N-bis[2-[bis(tert-butoxycarbonylmethyl)amino]ethyl]glycine; A protected DTPA derivative; Nitrobenzyl-DTPA penta-t-butyl ester; Chelator intermediate; 262855-60-7
EINECS	Contact for details

Quality Control

Our S-2-(4-Nitrobenzyl)-Diethylenetriamine Penta-T-Butyl Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.