Description

2-[3-(Difluoromethoxy)Phenyl]Acetic Acid is a high-purity, synthetically valuable aromatic acetic acid derivative characterized by its unique difluoromethoxy substituent. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the introduction of specific fluorinated motifs into target molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used as a building block for developing advanced herbicides and fungicides, where the difluoromethoxy group can enhance biological activity and stability.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of compound libraries for high-throughput screening.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalytic processes and material science.
• Fluorinated Compound Research: Essential for academic and industrial research focused on the properties and applications of organofluorine chemistry.

Basic Information

Product Name	2-[3-(Difluoromethoxy)Phenyl]Acetic Acid
CAS No.	262587-06-4
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	3-(Difluoromethoxy)phenylacetic Acid; [3-(Difluoromethoxy)phenyl]acetic Acid; α-(3-Difluoromethoxyphenyl)acetic Acid; 2-(3-(Difluoromethoxy)phenyl)acetic Acid; DFMPAA; 262587-06-4; Acetic acid, 2-[3-(difluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 2-[3-(Difluoromethoxy)Phenyl]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and batch-to-batch consistency for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and heat sources. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.