Description

2-Amino-4,4,4-Trifluorobutanoic Acid Hydrochloride is a high-purity, non-natural amino acid derivative of significant interest in advanced chemical synthesis. This compound serves as a critical fluorinated building block, enabling the introduction of a trifluoromethyl group and a chiral amino acid backbone into target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated drug candidates, including protease inhibitors and enzyme modulators.
• Agrochemical Synthesis: Used in the creation of advanced, fluorinated pesticides and herbicides where the trifluoromethyl group enhances biological activity and stability.
• Peptide Chemistry: Incorporated into custom peptides to study structure-activity relationships (SAR) and to create metabolically stable analogs.
• Chemical Biology Probes: Serves as a building block for fluorinated amino acid analogs used in probing enzyme mechanisms and protein interactions.
• Material Science Research: Potential monomer or modifier for creating specialized polymers with unique surface properties or stability.
• Academic & Industrial R&D: Fundamental reagent for methodological development in asymmetric synthesis and fluorine chemistry.

Basic Information

Product Name	2-Amino-4,4,4-Trifluorobutanoic Acid Hydrochloride
CAS No.	262296-39-9
Molecular Formula	C4H7F3NO2 • HCl
Molecular Weight	197.56 g/mol (Free base: 161.10 g/mol)
Synonyms	4,4,4-Trifluoro-DL-norvaline hydrochloride; 2-Amino-4,4,4-trifluorobutanoic acid HCl; DL-4,4,4-Trifluoronorvaline hydrochloride; (±)-2-Amino-4,4,4-trifluorobutyric acid hydrochloride; 4,4,4-Trifluoro-2-aminobutanoic acid hydrochloride; 2-Azaniumyl-4,4,4-trifluorobutanoate chloride
EINECS	Contact for details

Quality Control

Our 2-Amino-4,4,4-Trifluorobutanoic Acid Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.