Description

4-Methyl-2-(Trifluoromethyl)Benzamide is a specialized fluorinated aromatic amide building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the benzamide scaffold and the electron-withdrawing trifluoromethyl group, which is crucial for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, where the introduction of fluorine atoms is a key strategy to enhance metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for novel fluorinated polymers, liquid crystals, or organic electronic materials with tailored properties.
• Chemical Biology Probe Development: Utilized as a building block for creating fluorinated analogs of bioactive molecules to study metabolic pathways and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring fluorinated aromatic compounds.

Basic Information

Product Name	4-Methyl-2-(Trifluoromethyl)Benzamide
CAS No.	261951-99-9
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	2-(Trifluoromethyl)-4-methylbenzamide; 4-Methyl-2-trifluoromethylbenzamide; α,α,α-Trifluoro-4-methyl-o-toluamide; 2-Trifluoromethyl-p-toluamide; Benzamide, 4-methyl-2-(trifluoromethyl)-; 4-Methyl-2-(trifluoromethyl)benzenecarboxamide
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-2-(Trifluoromethyl)Benzamide adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistency and compliance with client specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.