Description

2-Methyl-4-(Trifluoromethoxy)Benzamide is a specialized benzamide derivative featuring a trifluoromethoxy substituent, a structural motif known for enhancing metabolic stability and lipophilicity. This compound is valued for its role as a critical synthetic intermediate in advanced organic synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this unique fluorinated building block into novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring enhanced bioavailability.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides where the trifluoromethoxy group can improve biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the development of advanced polymers, liquid crystals, or organic electronic materials with specific fluorinated properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function or biological pathways.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Methyl-4-(Trifluoromethoxy)Benzamide
CAS No.	261951-90-0
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	2-Methyl-4-(trifluoromethoxy)benzamide; 4-(Trifluoromethoxy)-2-methylbenzamide; 2-Methyl-4-trifluoromethoxybenzamide; Benzamide, 2-methyl-4-(trifluoromethoxy)-; α-Methyl-4-(trifluoromethoxy)benzamide; 2-Methyl-4-(trifluoromethoxy)benzoic acid amide
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(Trifluoromethoxy)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.