Description

2,3-Difluoro-4-Methylbenzamide is a high-purity fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its core value lies in its unique substitution pattern, which makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, where it serves as a key precursor in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, where the difluoro-methylbenzamide moiety can contribute to improved efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and liquid crystals, imparting specific electronic or thermal properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to introduce the difluoromethylbenzene unit into more complex molecular architectures.
• Fluorine Chemistry Studies: Acts as a model compound in academic and industrial research focused on the behavior and reactivity of difluorinated arenes.

Basic Information

Product Name	2,3-Difluoro-4-Methylbenzamide
CAS No.	261763-35-3
Molecular Formula	C8H7F2NO
Molecular Weight	171.15 g/mol
Synonyms	2,3-Difluoro-4-methylbenzamide; 4-Methyl-2,3-difluorobenzamide; Benzamide, 2,3-difluoro-4-methyl-; 2,3-Difluoro-p-toluamide; 2,3-Difluoro-4-methyl-benzoic acid amide; 261763-35-3; 4-Methyl-2,3-difluorobenzoic acid amide
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methylbenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.