Description

5-Fluoro-1-[(2-Nitrophenyl)Methyl]-1H-Indole is a specialized indole derivative, a high-value chemical intermediate designed for advanced synthetic chemistry. This compound matters for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate unique fluorinated and nitrated indole scaffolds into their target compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the indole and nitroaromatic motifs.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.
• Ligand & Catalyst Development: Utilized to construct complex ligands for catalysis or as a scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-Fluoro-1-[(2-Nitrophenyl)Methyl]-1H-Indole
CAS No.	261762-12-3
Molecular Formula	C15H11FN2O2
Molecular Weight	270.26 g/mol
Synonyms	1-[(2-Nitrophenyl)methyl]-5-fluoro-1H-indole; 5-Fluoro-1-(2-nitrobenzyl)-1H-indole; 5-Fluoro-1-(2-nitrobenzyl)indole; 1H-Indole, 5-fluoro-1-[(2-nitrophenyl)methyl]-; 261762-12-3; 5-Fluoro-1-(o-nitrobenzyl)indole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-[(2-Nitrophenyl)Methyl]-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.