Description

4-Methylisoxazole-5-Carboxylic Acid is a versatile heterocyclic carboxylic acid building block, essential for advanced organic synthesis and pharmaceutical research. Its core value lies in its functionalized isoxazole ring, which serves as a key precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the bioactivity of the isoxazole moiety.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and organic electronic materials due to its rigid heterocyclic structure.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	4-Methylisoxazole-5-Carboxylic Acid
CAS No.	261350-46-3
Molecular Formula	C5H5NO3
Molecular Weight	127.10 g/mol
Synonyms	5-Carboxy-4-methylisoxazole; 4-Methyl-1,2-oxazole-5-carboxylic acid; 4-Methyl-5-isoxazolecarboxylic acid; 4-Methylisoxazole-5-carboxylic acid; 4-Methyl-5-carboxyisoxazole; 5-Isoxazolecarboxylic acid, 4-methyl-; AI3-52220; CTK8G7231
EINECS	Contact for details

Quality Control

Our 4-Methylisoxazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.