Description

Cyclohexylmethyl- -D-Maltoside 500M is a high-purity, non-ionic detergent specifically designed for membrane protein research and solubilization. This compound is critical for stabilizing and extracting integral membrane proteins in their native, functional state for structural and biochemical analysis. It is an essential reagent for researchers and process developers in the biopharmaceutical, structural biology, and life science research sectors.

Application

• Membrane Protein Solubilization: For the effective extraction of integral membrane proteins from lipid bilayers while maintaining protein activity.
• Protein Stabilization: Used to stabilize purified membrane proteins in aqueous solution for downstream applications like crystallization and functional assays.
• Structural Biology: A key detergent in the preparation of samples for X-ray crystallography, cryo-electron microscopy (cryo-EM), and NMR spectroscopy.
• Biopharmaceutical Development: Employed in the research and development of therapeutics targeting membrane proteins, such as G protein-coupled receptors (GPCRs).
• Liposome and Vesicle Preparation: Useful in the formation and manipulation of model membrane systems for biophysical studies.
• Cell Lysis: Can be utilized in gentle lysis buffers for the isolation of membrane-bound organelles and complexes.

Basic Information

Product Name	Cyclohexylmethyl- -D-Maltoside 500M
CAS No.	260804-64-6
Molecular Formula	C19H36O11
Molecular Weight	440.49 g/mol
Synonyms	Cyclohexylmethyl β-D-maltoside; CHM-Maltoside; Cyclohexylmethyl-β-D-maltopyranoside; 4-O-α-D-Glucopyranosyl-β-D-glucopyranoside, cyclohexylmethyl; CHM; Detergent CHM; Cyclohexylmethyl maltoside; n-Cyclohexylmethyl-β-D-maltoside
EINECS	Contact for details

Quality Control

Our Cyclohexylmethyl- -D-Maltoside 500M is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot is tested to confirm identity, purity, and critical micelle concentration (CMC). A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), critical parameters, and test results is provided with every shipment to support your research and quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a desiccated environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Critical Micelle Concentration (CMC)	Contact for details
pH (1% Solution)	5.0 - 7.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.