Description

5,6-Difluoro-1H-Indole-3-Carboxaldehyde is a high-value fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which is essential for constructing complex molecules with tailored biological and electronic properties. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atoms enhance bioavailability and stability.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent due to the reactivity of the aldehyde group.
• Academic & R&D: Fundamental research in heterocyclic and fluorine chemistry for novel compound libraries.

Basic Information

Product Name	5,6-Difluoro-1H-Indole-3-Carboxaldehyde
CAS No.	260267-07-0
Molecular Formula	C9H5F2NO
Molecular Weight	181.14 g/mol
Synonyms	5,6-Difluoroindole-3-carboxaldehyde; 3-Formyl-5,6-difluoro-1H-indole; 5,6-Difluoro-1H-indole-3-carbaldehyde; 1H-Indole-3-carboxaldehyde, 5,6-difluoro-; 260267-07-0; 5,6-Difluoroindole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5,6-Difluoro-1H-Indole-3-Carboxaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.