Description

Cucurbit(8)Uril (CAS NO 259886-51-6) is a synthetic macrocyclic host molecule belonging to the cucurbit[n]uril family, characterized by its rigid, barrel-shaped cavity with two identical carbonyl-laced portals. This unique structure enables the formation of exceptionally stable host-guest complexes with a wide range of organic molecules, ions, and polymers, making it a cornerstone for advanced supramolecular chemistry. It is essential for researchers and product developers in pharmaceuticals, materials science, and nanotechnology who require precise molecular recognition, controlled assembly, and stimuli-responsive systems.

Application

• Supramolecular Assembly & Smart Materials: As a key building block for constructing complex, self-assembled nanostructures, hydrogels, and stimuli-responsive materials.
• Pharmaceutical Sciences & Drug Delivery: For enhancing drug solubility, stability, and bioavailability through encapsulation, and for creating targeted, controlled-release systems.
• Catalysis: To create microreactor environments within its cavity, facilitating unique reaction pathways and enhancing catalytic selectivity and efficiency.
• Sensing & Detection: In the development of highly sensitive and selective chemical sensors and biosensors based on fluorescence quenching/enhancement or colorimetric changes upon guest binding.
• Wastewater Treatment: For the selective capture and removal of organic pollutants, dyes, and specific metal ions from industrial effluents.
• Surface Modification & Coatings: To functionalize surfaces for non-fouling, antimicrobial, or specific adhesion properties through host-guest interactions.
• Analytical Chemistry: As a stationary phase modifier in chromatography for the separation of challenging isomers or enantiomers.
• Fundamental Research: A critical tool for studying non-covalent interactions, molecular recognition, and the principles of supramolecular chemistry.

Basic Information

Item	Details
Product Name	Cucurbit(8)Uril
CAS No.	259886-51-6
Molecular Formula	C48H48N32O16
Molecular Weight	1329.06 g/mol
Synonyms	CB[8]; Cucurbit[8]uril; 1,3,5,7,9,11,13,15-Octaazapentacyclo[13.13.13.13,7.19,13]octacosane, Glycoluril Homooctamer; Macrocyclic Glycoluril Octamer; Host Molecule CB8
EINECS	Contact for details

Quality Control

Our Cucurbit(8)Uril is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and TGA for thermal stability assessment. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption, which can affect performance. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.