Description

6-tert-Butyl 2-Methyl 7,8-Dihydro-1,6-Naphthyridine-2,6(5H)-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the naphthyridine class of heterocyclic compounds. Its value lies in its role as a critical building block for synthesizing complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• API Synthesis: Used as a core scaffold or fragment for constructing complex Active Pharmaceutical Ingredients (APIs) with naphthyridine-based structures.
• Medicinal Chemistry Research: A valuable building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Development & Scale-up: Employed in optimizing synthetic routes from laboratory scale to pilot plant and commercial manufacturing.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals for advanced material science and agrochemical applications.

Basic Information

Product Name	6-tert-Butyl 2-Methyl 7,8-Dihydro-1,6-Naphthyridine-2,6(5H)-Dicarboxylate
CAS No.	259809-47-7
Molecular Formula	C16H22N2O4
Molecular Weight	306.36 g/mol
Synonyms	6-tert-Butyl 2-methyl 5,6,7,8-tetrahydro-1,6-naphthyridine-2,6-dicarboxylate; 2,6-Dicarboxylic acid, 7,8-dihydro-1,6-naphthyridine-, 6-(1,1-dimethylethyl) 2-methyl ester; Methyl 6-(tert-butoxycarbonyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate; tert-Butyl methyl 7,8-dihydro-1,6-naphthyridine-2,6(5H)-dicarboxylate; BOC-protected naphthyridine ester; CAS 259809-47-7
EINECS	Contact for details

Quality Control

Our 6-tert-Butyl 2-Methyl 7,8-Dihydro-1,6-Naphthyridine-2,6(5H)-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.