Description

2-Amino-3-Bromo-5-Fluorobenzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, bromo, and fluoro substituents, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-cancer agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, where the halogen and amino groups contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a derivatization reagent or a scaffold for designing molecular probes and enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	2-Amino-3-Bromo-5-Fluorobenzoic Acid
CAS No.	259269-84-6
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.03 g/mol
Synonyms	3-Bromo-5-fluoroanthranilic acid; 2-Amino-3-bromo-5-fluorobenzoic acid; Benzoic acid, 2-amino-3-bromo-5-fluoro-; 5-Fluoro-3-bromoanthranilic acid; 3-Bromo-5-fluoro-2-aminobenzoic acid; 2-Azanyl-3-bromo-5-fluorobenzoic acid (IUPAC); ABFBA (abbreviation)
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Bromo-5-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.