Description

1-[2,6-Dichloro-4-(Fluoromethyl)Phenyl]-3-Methyl-1H-Pyrazole-5-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate critical for the synthesis of modern active pharmaceutical ingredients (APIs). This compound is valued for its precise chemical structure, which serves as a key building block in the development of novel therapeutic agents. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for process development and commercial-scale production.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the manufacture of active pharmaceutical ingredients (APIs), particularly for novel drug candidates.
• Agrochemical Research: Used in the research and development of new-generation pesticides and herbicides, leveraging its pyrazole core structure.
• Chemical Synthesis: Serves as a versatile building block for constructing complex organic molecules in medicinal chemistry.
• Process Development: Employed in process chemistry for route scouting, optimization, and scale-up studies in pilot plants.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of client-specific target molecules.
• Academic & Industrial R&D: Utilized in research laboratories for studying structure-activity relationships (SAR) and developing new chemical entities.

Basic Information

Item	Details
Product Name	1-[2,6-Dichloro-4-(Fluoromethyl)Phenyl]-3-Methyl-1H-Pyrazole-5-Carboxylic Acid Ethyl Ester
CAS No.	259243-71-5
Molecular Formula	C14H13Cl2FN2O2
Molecular Weight	331.17 g/mol
Synonyms	Ethyl 1-[2,6-dichloro-4-(fluoromethyl)phenyl]-3-methyl-1H-pyrazole-5-carboxylate; 1-[2,6-Dichloro-4-(fluoromethyl)phenyl]-3-methyl-1H-pyrazole-5-carboxylic acid ethyl ester; 259243-71-5; Ethyl 3-methyl-1-[2,6-dichloro-4-(fluoromethyl)phenyl]pyrazole-5-carboxylate; 1H-Pyrazole-5-carboxylic acid, 1-[2,6-dichloro-4-(fluoromethyl)phenyl]-3-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of 1-[2,6-Dichloro-4-(Fluoromethyl)Phenyl]-3-Methyl-1H-Pyrazole-5-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support audits and regulatory documentation for cGMP compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.