Description

Quinoline, 8-[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]- is a specialized chiral quinoline derivative featuring an oxazoline moiety, serving as a high-value building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where its specific stereochemistry and functional groups enable the creation of complex, biologically active molecules. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise, high-purity intermediates for asymmetric synthesis and catalyst development.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical control.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the quinoline-oxazoline structure can contribute to specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical and Specialty Chemical Production: Employed in the manufacture of complex molecules for electronics, materials science, and other high-tech applications.
• Academic and Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in medicinal chemistry and synthetic methodology.

Basic Information

Product Name	Quinoline, 8-[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-
CAS No.	259105-54-9
Molecular Formula	C15H18N2O
Molecular Weight	242.32 g/mol
Synonyms	(4R)-4-Isopropyl-2-(quinolin-8-yl)-4,5-dihydrooxazole; 8-[(4R)-4-Isopropyl-4,5-dihydro-1,3-oxazol-2-yl]quinoline; (R)-4-Isopropyl-2-(quinolin-8-yl)-4,5-dihydrooxazole; (R)-8-(4-Isopropyl-4,5-dihydrooxazol-2-yl)quinoline; Chiral Quinoline-Oxazoline Ligand Precursor; (R)-Quinox
EINECS	Contact for details

Quality Control

Our Quinoline, 8-[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.