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1,3-Bis(2,6-Diisopropylphenyl)-Imidazolidinium-Chloride CAS NO 258278-25-0


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CAS No.:258278-25-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,3-Bis(2,6-Diisopropylphenyl)-Imidazolidinium-Chloride is a high-purity, advanced N-heterocyclic carbene (NHC) precursor salt, essential for modern organometallic catalysis. This compound matters because it serves as a critical ligand source for generating highly active and selective transition metal catalysts used in fine chemical and pharmaceutical synthesis. Industrial researchers and process chemists in the pharmaceutical, agrochemical, and specialty polymer sectors require this material for developing efficient cross-coupling, polymerization, and hydrogenation reactions.

Application

  • Precursor for generating N-heterocyclic carbene (NHC) ligands in organometallic chemistry.
  • Key component in the synthesis of ruthenium-based catalysts for olefin metathesis reactions (e.g., Grubbs-type catalysts).
  • Ligand for palladium-catalyzed cross-coupling reactions (Suzuki, Heck, Negishi) in API intermediate manufacturing.
  • Building block for specialized ionic liquids and phase-transfer catalysts.
  • Used in R&D for developing novel catalysts for asymmetric synthesis and C-H activation.
  • Component in catalyst systems for ring-opening polymerization (ROP) to produce biodegradable polymers.

Basic Information

Product Name 1,3-Bis(2,6-Diisopropylphenyl)-Imidazolidinium-Chloride
CAS No. 258278-25-0
Molecular Formula C29H43ClN2
Molecular Weight 455.12 g/mol
Synonyms 1,3-Bis(2,6-diisopropylphenyl)imidazolidinium chloride; SIPr·HCl; 1,3-Bis(2,6-diisopropylphenyl)-4,5-dihydroimidazolium chloride; N,N'-Bis(2,6-diisopropylphenyl)imidazolidinium chloride; Imidazolidinium, 1,3-bis(2,6-diisopropylphenyl)-, chloride; NHC precursor SIPr-HCl; Saturated NHC salt; 1,3-Di(2,6-diisopropylphenyl)imidazolidinium chloride
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Quality Control

Our 1,3-Bis(2,6-Diisopropylphenyl)-Imidazolidinium-Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ISO 9001 standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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