Description

6-Hydroxybicyclo[2.2.2]octane-2-carboxylic acid is a highly functionalized, rigid bicyclic carboxylic acid derivative, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its unique sterically constrained structure makes it particularly significant for constructing complex molecular architectures with precise three-dimensional control. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging its rigid scaffold for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Monomer: Employed in polymer chemistry to introduce rigid, functional groups into specialty polymers for high-performance applications.
• Chemical Research: A versatile building block in academic and industrial R&D for exploring new synthetic methodologies and compound libraries.
• Flavor and Fragrance Chemistry: Potential intermediate for synthesizing complex odorants and flavor compounds with unique sensory profiles.

Basic Information

Product Name	6-Hydroxybicyclo[2.2.2]octane-2-carboxylic Acid
CAS No.	257932-17-5
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	6-Hydroxybicyclo[2.2.2]octane-2-carboxylic acid; 2-Bicyclo[2.2.2]octanecarboxylic acid, 6-hydroxy-; 6-Hydroxy-2-bicyclo[2.2.2]octanecarboxylic acid; 6-Hydroxy-2-norbornanecarboxylic acid (related structural name); Bicyclo[2.2.2]octane-2-carboxylic acid, 6-hydroxy-; 6-Hydroxy-BCO-2-CA; 6-OH-BCO-2-COOH
EINECS	Contact for details

Quality Control

Our production of 6-Hydroxybicyclo[2.2.2]octane-2-carboxylic acid adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades from technical to research (>98%) based on customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Research Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.