Description

2-{1-[3-(tert-Butyl-Dimethyl-Silanyloxy)-Propyl]-1H-Indol-3-Yl}-Acetamide is a high-value, protected indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is essential for researchers and manufacturers requiring precise molecular building blocks for complex synthesis. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indole core structure for biological activity.
• Organic Synthesis: Serves as a versatile precursor for constructing more complex heterocyclic compounds and natural product analogs.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological research.
• Material Science: Potential intermediate for specialty polymers and advanced organic electronic materials.
• Process Development: Used in route scouting and optimization for the scalable production of fine chemicals.

Basic Information

Product Name	2-{1-[3-(tert-Butyl-Dimethyl-Silanyloxy)-Propyl]-1H-Indol-3-Yl}-Acetamide
CAS No.	257874-86-5
Molecular Formula	C19H30N2O2Si
Molecular Weight	346.55 g/mol
Synonyms	2-[1-[3-[(tert-Butyldimethylsilyl)oxy]propyl]-1H-indol-3-yl]acetamide; 2-(1-(3-((tert-Butyldimethylsilyl)oxy)propyl)-1H-indol-3-yl)acetamide; TBDMS-protected Indole-3-acetamide Derivative; N-[2-(1H-Indol-3-yl)ethyl]-3-[(tert-butyldimethylsilyl)oxy]propanamide (related); 257874-86-5; tert-Butyldimethyl(3-(3-(2-amino-2-oxoethyl)-1H-indol-1-yl)propoxy)silane
EINECS	Contact for details

Quality Control

Our 2-{1-[3-(tert-Butyl-Dimethyl-Silanyloxy)-Propyl]-1H-Indol-3-Yl}-Acetamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.