Description

Tricyclo[3.2.1.02,4]Octane-6-Carbonitrile, 3-Acetyl-, (1R,2R,3S,4S,5R,6R)-Rel- (9Ci) is a highly specialized, stereochemically defined organic building block with a complex, rigid polycyclic framework. This compound is valued for its precise three-dimensional structure, which makes it a critical intermediate in advanced synthetic chemistry, particularly for constructing molecules with specific spatial orientations. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a sophisticated chiral synthon for the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders or requiring complex molecular architectures.
• Agrochemical Research: Used in the synthesis of novel, high-performance pesticides and herbicides where the rigid tricyclic core can impart unique biological activity and stability.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for the synthesis of chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal and mechanical properties due to its strained, polycyclic structure.
• Academic & Process Chemistry: Employed in university and industrial labs for methodological studies, total synthesis of natural products, and scaling up complex synthetic routes.

Basic Information

Item	Detail
Product Name	Tricyclo[3.2.1.02,4]Octane-6-Carbonitrile, 3-Acetyl-, (1R,2R,3S,4S,5R,6R)-Rel- (9Ci)
CAS No.	256398-14-8
Molecular Formula	C11H13NO
Molecular Weight	175.23 g/mol
Synonyms	rel-(1R,2R,3S,4S,5R,6R)-3-Acetyltricyclo[3.2.1.02,4]octane-6-carbonitrile; 3-Acetyl-tricyclo[3.2.1.02,4]octane-6-carbonitrile, rel-(1R,2R,3S,4S,5R,6R)-; (1R,2R,3S,4S,5R,6R)-rel-3-Acetyltricyclo[3.2.1.02,4]octane-6-carbonitrile; Tricyclo[3.2.1.02,4]octane-6-carbonitrile, 3-acetyl-, (1R,2R,3S,4S,5R,6R)-rel-; 256398-14-8
EINECS	Contact for details

Quality Control

Our Tricyclo[3.2.1.02,4]Octane-6-Carbonitrile, 3-Acetyl-, (1R,2R,3S,4S,5R,6R)-Rel- (9Ci) is produced under strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) are provided, detailing results from techniques such as HPLC, GC, NMR, and chiral analysis. We support cGMP compliance for advanced intermediates and can tailor specifications to meet specific research or project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.