Description

Tricyclo[3.2.1.02,4]Octane-6-Carbonitrile, 3-Acetyl-, (1R,2R,3S,4S,5R,6S)-Rel- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its complex, rigid tricyclic framework, which serves as a critical chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing innovative therapeutics, particularly in areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Synthesis: Used as a sophisticated starting material or intermediate in complex asymmetric synthesis routes due to its defined stereochemistry.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes to explore new chemical entities.
• Process Chemistry Development: Serves as a benchmark or intermediate in scaling up synthetic pathways from laboratory to pilot plant scale.
• Academic & Industrial R&D: Utilized in cutting-edge organic chemistry research for methodology development and the construction of complex natural product analogs.

Basic Information

Product Name	Tricyclo[3.2.1.02,4]Octane-6-Carbonitrile, 3-Acetyl-, (1R,2R,3S,4S,5R,6S)-Rel- (9Ci)
CAS No.	256398-13-7
Molecular Formula	C11H13NO
Molecular Weight	175.23 g/mol
Synonyms	rel-(1R,2R,3S,4S,5R,6S)-3-Acetyltricyclo[3.2.1.02,4]octane-6-carbonitrile; 3-Acetyltricyclo[3.2.1.02,4]octane-6-carbonitrile, rel-(1R,2R,3S,4S,5R,6S)-; (1R,2R,3S,4S,5R,6S)-rel-3-Acetyl-tricyclo[3.2.1.02,4]octane-6-carbonitrile; Tricyclo[3.2.1.02,4]octane-6-carbonitrile, 3-acetyl-, (1R,2R,3S,4S,5R,6S)-rel-; CAS 256398-13-7
EINECS	Contact for details

Quality Control

Every batch of Tricyclo[3.2.1.02,4]Octane-6-Carbonitrile, 3-Acetyl-, (1R,2R,3S,4S,5R,6S)-Rel- (9Ci) is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity and compliance with customer specifications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Consider storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.