Description

Ethyl 4-Oxo-7-(Trifluoromethyl)-4H-Pyrido[1,2-A]Pyrimidine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drugs and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides and pesticides, leveraging the biological activity of the pyridopyrimidine core.
• Organic Synthesis: Used in academic and industrial laboratories for constructing complex heterocyclic compounds and studying structure-activity relationships (SAR).
• Material Science: Potential application in the development of organic electronic materials and specialty dyes due to its conjugated system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	Ethyl 4-Oxo-7-(Trifluoromethyl)-4H-Pyrido[1,2-A]Pyrimidine-3-Carboxylate
CAS No.	256238-90-1
Molecular Formula	C12H9F3N2O3
Molecular Weight	286.21 g/mol
Synonyms	Ethyl 7-(Trifluoromethyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylate; 4H-Pyrido[1,2-a]pyrimidine-3-carboxylic acid, 4-oxo-7-(trifluoromethyl)-, ethyl ester; 7-Trifluoromethyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid ethyl ester; Ethyl 4-oxo-7-trifluoromethyl-4H-pyrido[1,2-a]pyrimidine-3-carboxylate; CAS 256238-90-1
EINECS	Contact for details

Quality Control

Our Ethyl 4-Oxo-7-(Trifluoromethyl)-4H-Pyrido[1,2-A]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.