Description

1-Thio-D-Glucose, Sodium Salt Hydrate is a chemically modified sugar derivative where a sulfur atom replaces the oxygen atom at the anomeric carbon. This compound is a valuable biochemical reagent and synthetic intermediate, prized for its ability to act as a glycosyl donor mimic or enzyme inhibitor in carbohydrate chemistry research. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing novel therapeutics, diagnostic tools, or studying metabolic pathways.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or building block in the synthesis of novel drug candidates, especially those targeting glycosidases or glycosyltransferases.
• Biochemical Studies: Used as a substrate analog or inhibitor to study enzyme mechanisms, carbohydrate metabolism, and cellular signaling pathways.
• Glycobiology: A crucial tool for probing and manipulating glycosylation processes, aiding in the development of glycoconjugate vaccines and biologics.
• Diagnostic Reagent Manufacturing: Employed in the production of specialized reagents for clinical diagnostics and research assays.
• Chemical Synthesis: Acts as a chiral synthon for the preparation of more complex thio-sugar derivatives and other fine chemicals.

Basic Information

Product Name	1-Thio-D-Glucose, Sodium Salt Hydrate
CAS No.	255818-98-5
Molecular Formula	C6H11NaO5S·xH2O
Molecular Weight	Anhydrous: 218.20 g/mol
Synonyms	Sodium 1-Thio-β-D-glucopyranoside Hydrate; 1-Thio-β-D-Glucose Sodium Salt Hydrate; 1-Thio-β-D-glucose sodium salt; Sodium 1-Thio-β-D-glucoside; Thio-D-glucose sodium salt; β-D-Glucopyranose, 1-thio-, sodium salt, hydrate
EINECS	Contact for details

Quality Control

Our 1-Thio-D-Glucose, Sodium Salt Hydrate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications and results is provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled, dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.