Description

6-Bromo-1H-Benzoimidazole-4-Carboxylic Acid is a high-purity, functionalized benzimidazole derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a reactive carboxylic acid group with a halogenated benzimidazole core, enabling precise modifications for creating novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting specific enzyme pathways where the benzimidazole scaffold is active.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators that require halogenated heterocyclic structures.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers, ligands for metal-organic frameworks (MOFs), and advanced organic electronic materials.
• Chemical Synthesis: Employed in medicinal and combinatorial chemistry for structure-activity relationship (SAR) studies and library synthesis due to its versatile reactive sites.
• Bioconjugation & Probe Development: The carboxylic acid group allows for coupling to biomolecules, making it useful for creating fluorescent probes or diagnostic agents.

Basic Information

Product Name	6-Bromo-1H-Benzoimidazole-4-Carboxylic Acid
CAS No.	255064-08-5
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	6-Bromo-1H-benzimidazole-4-carboxylic acid; 6-Bromo-1H-benzo[d]imidazole-4-carboxylic acid; 4-Carboxy-6-bromobenzimidazole; 6-Bromo-4-carboxybenzimidazole; 255064-08-5; 6-Bromo-1H-benzoimidazole-4-carboxylic acid; Benzoimidazole-4-carboxylic acid, 6-bromo-; 6-Bromobenzimidazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-1H-Benzoimidazole-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for all critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.