Description

(1R,2R)-1-Amino-1-Phenylpropan-2-Ol Hydrochloride is a high-purity chiral intermediate and building block of significant importance in advanced organic synthesis. Its value lies in its well-defined stereochemistry, which is critical for producing enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality chiral synthons.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis Catalyst/Precursor: Used in the preparation of chiral ligands or catalysts for asymmetric hydrogenation and other stereoselective transformations.
• Agrochemical Research: Serves as a precursor for developing chiral active ingredients in herbicides, fungicides, and insecticides.
• Academic & Industrial R&D: A valuable compound for methodological development in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.

Basic Information

Item	Detail
Product Name	(1R,2R)-1-Amino-1-Phenylpropan-2-Ol Hydrochloride
CAS No.	255060-27-6
Molecular Formula	C9H14ClNO
Molecular Weight	187.67 g/mol
Synonyms	(1R,2R)-(-)-2-Amino-1-phenyl-1-propanol hydrochloride; (1R,2R)-1-Phenyl-2-aminopropan-1-ol hydrochloride; (1R,2R)-Norephedrine hydrochloride; (1R,2R)-Threo-1-phenyl-2-aminopropan-1-ol hydrochloride; d-Threo-Norephedrine HCl; (1R,2R)-1-Phenyl-1-hydroxy-2-propylamine hydrochloride; (1R,2R)-α-(1-Aminoethyl)benzyl alcohol hydrochloride
EINECS	Contact for details

Quality Control

Our (1R,2R)-1-Amino-1-Phenylpropan-2-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.