Description

2-Methyl-2-[3-(Trifluoromethyl)Phenyl]Propanoic Acid CAS NO 254895-42-6 is a high-value trifluoromethylated aromatic compound, a key building block in modern synthetic chemistry. Its unique structure, featuring a sterically hindered carboxylic acid adjacent to a trifluoromethylphenyl group, makes it an essential intermediate for creating molecules with enhanced metabolic stability and lipophilicity. This compound is primarily sought after by pharmaceutical and agrochemical research and development teams for the synthesis of advanced active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorine-substituted molecules for improved bioavailability and target binding.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group confers enhanced biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated components for liquid crystal displays (LCDs), contributing to improved dielectric anisotropy and stability.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials for OLEDs and photovoltaic applications.
• Advanced Polymer Modifiers: Acts as a monomer or functionalization agent for creating specialty polymers with specific surface properties, chemical resistance, or optical characteristics.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new reaction pathways and creating compound libraries for high-throughput screening.

Basic Information

Product Name	2-Methyl-2-[3-(Trifluoromethyl)Phenyl]Propanoic Acid
CAS No.	254895-42-6
Molecular Formula	C11H11F3O2
Molecular Weight	232.20 g/mol
Synonyms	α,α-Dimethyl-3-(trifluoromethyl)benzenepropanoic Acid; 2-Methyl-2-(3-trifluoromethylphenyl)propionic Acid; 3-(Trifluoromethyl)hydratropic Acid; 2-(3-(Trifluoromethyl)phenyl)-2-methylpropanoic Acid; Benzenepropanoic acid, α,α-dimethyl-3-(trifluoromethyl)-; MTPA (3-Trifluoromethyl derivative); 2-Methyl-2-(m-trifluoromethylphenyl)propionic Acid
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-2-[3-(Trifluoromethyl)Phenyl]Propanoic Acid adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC, to ensure consistency and meet the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.