Description

2-Furanmethanol, 5-Ethynyltetrahydro-, (2S,5S)- (9Ci) is a high-value, stereochemically defined chiral building block featuring both a furan ring and an ethynyl group. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, as well as by specialty chemical manufacturers developing advanced materials and catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of new active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials due to its reactive ethynyl group.
• Fine Chemical Production: Acts as a versatile building block for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Furanmethanol, 5-Ethynyltetrahydro-, (2S,5S)- (9Ci)
CAS No.	254891-67-3
Molecular Formula	C7H8O2
Molecular Weight	124.14 g/mol
Synonyms	(2S,5S)-5-Ethynyltetrahydrofurfuryl Alcohol; (2S,5S)-5-Ethynyltetrahydro-2-furanmethanol; 5-Ethynyltetrahydro-2-furanmethanol, (2S,5S)-; Tetrahydro-5-ethynyl-2-furanmethanol, (2S-cis)-; Chiral Ethynyl Furan Alcohol; (2S,5S)-5-Ethynyloxolane-2-methanol
EINECS	Contact for details

Quality Control

Our (2S,5S)-5-Ethynyltetrahydrofurfuryl Alcohol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific parameters.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.