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Methyl-8-Bromoquinoline-5-Carboxylate CAS NO 253787-45-0


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CAS No.:253787-45-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl-8-Bromoquinoline-5-Carboxylate is a high-purity brominated quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality building blocks for drug discovery and specialty chemical synthesis.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting infectious diseases or central nervous system disorders.
  • Agrochemical Research: Used in the development of novel fungicides, herbicides, and insecticides, leveraging the bioactivity of the quinoline core.
  • Material Science: Serves as a building block for creating organic ligands in catalysis or for synthesizing functional organic materials with specific electronic properties.
  • Chemical Biology: Employed as a molecular probe or tag in biochemical assays due to its fluorescent quinoline structure and reactive bromine site.
  • Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Item Detail
Product Name Methyl-8-Bromoquinoline-5-Carboxylate
CAS No. 253787-45-0
Molecular Formula C11H8BrNO2
Molecular Weight 266.09 g/mol
Synonyms Methyl 8-bromoquinoline-5-carboxylate; 8-Bromo-quinoline-5-carboxylic acid methyl ester; 5-Quinolinecarboxylic acid, 8-bromo-, methyl ester; Methyl 8-bromo-5-quinolinecarboxylate; 8-Bromoquinoline-5-carboxylic Acid Methyl Ester
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Quality Control

Our Methyl-8-Bromoquinoline-5-Carboxylate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Residual Solvents (GC) Complies with ICH guidelines
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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