Description

2-(1H-1,2,4-Triazol-5-Ylsulfanyl)Propanoic Acid is a high-purity, sulfur-containing heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring a triazole ring linked via a thioether to a propanoic acid group, makes it a versatile intermediate for creating compounds with specific biological or material science functionalities. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the triazole-thioether motif can enhance binding affinity or modulate pharmacokinetic properties.
• Agrochemical Synthesis: Building block for developing new generation fungicides, herbicides, or plant growth regulators that leverage its heterocyclic structure for targeted biological activity.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalysis, leveraging the sulfur and nitrogen donor atoms for metal coordination.
• Material Science Research: Intermediate for synthesizing functional polymers or small molecules with potential applications in electronics, coatings, or as corrosion inhibitors.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological processes, utilizing the carboxylic acid for conjugation to other molecules.

Basic Information

Product Name	2-(1H-1,2,4-Triazol-5-Ylsulfanyl)Propanoic Acid
CAS No.	253779-17-8
Molecular Formula	C5H7N3O2S
Molecular Weight	173.19 g/mol
Synonyms	2-[(1H-1,2,4-Triazol-5-yl)thio]propanoic acid; 2-(1H-1,2,4-Triazol-5-ylsulfanyl)propionic acid; 5-[(1-Carboxyethyl)thio]-1H-1,2,4-triazole; 2-(1H-1,2,4-Triazol-5-ylthio)propanoic acid; Propanoic acid, 2-[(1H-1,2,4-triazol-5-yl)thio]-; 253779-17-8
EINECS	Contact for details

Quality Control

Our 2-(1H-1,2,4-Triazol-5-Ylsulfanyl)Propanoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.