Description

2-tert-Butoxycarbonylamino-5-Chloro-Benzoic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules. It is primarily utilized by pharmaceutical R&D departments, fine chemical manufacturers, and academic research institutions focused on peptide chemistry and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Peptide Synthesis: Used as a protected amino acid derivative for the solid-phase and solution-phase synthesis of custom peptides and peptidomimetics.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of novel enzyme inhibitors.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the development of molecular probes and tags.
• Agrochemical Synthesis: Acts as an intermediate in the creation of advanced, high-performance crop protection agents with specific modes of action.
• Material Science: A potential monomer or precursor for specialty polymers and functionalized surfaces requiring specific chemical handles.

Basic Information

Product Name	2-tert-Butoxycarbonylamino-5-Chloro-Benzoic Acid
CAS No.	253677-29-1
Molecular Formula	C₁₂H₁₄ClNO₄
Molecular Weight	271.70 g/mol
Synonyms	5-Chloro-2-[(tert-butoxycarbonyl)amino]benzoic acid; Boc-5-Cl-Anthranilic Acid; 2-((tert-Butoxycarbonyl)amino)-5-chlorobenzoic acid; 2-(Boc-amino)-5-chlorobenzoic acid; 2-Amino-5-chlorobenzoic acid N-Boc derivative; t-BOC-5-Chloroanthranilic Acid; N-Boc-5-chloroanthranilic acid; 5-Chloro-N-Boc-anthranilic acid
EINECS	Contact for details

Quality Control

Every batch of 2-tert-Butoxycarbonylamino-5-Chloro-Benzoic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical and research applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable consistency and traceability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.