Description

6-Chloro-3,4-Dihydro-4-Hydroxy-3-(Phenylsulfonyl)-4-(Trifluoromethyl)-2(1H)-Quinolinone is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its complex molecular architecture, featuring a quinolinone core with chloro, hydroxy, phenylsulfonyl, and trifluoromethyl substituents, makes it a critical intermediate for developing novel bioactive compounds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new chemical entities with potential therapeutic or pesticidal activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, anti-inflammatory drugs, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the discovery and synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinolinone scaffold and the properties of the trifluoromethyl group.
• Chemical Research & Development: Acts as a versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the exploration of new heterocyclic compound libraries.
• Material Science Research: Investigated for potential use in the development of advanced organic materials, such as organic semiconductors or ligands for catalytic systems.

Basic Information

Product Name	6-Chloro-3,4-Dihydro-4-Hydroxy-3-(Phenylsulfonyl)-4-(Trifluoromethyl)-2(1H)-Quinolinone
CAS No.	253663-82-0
Molecular Formula	C₁₆H₁₁ClF₃NO₄S
Molecular Weight	405.78 g/mol
Synonyms	6-Chloro-4-hydroxy-3-(phenylsulfonyl)-4-(trifluoromethyl)-3,4-dihydro-2(1H)-quinolinone; 6-Chloro-4-hydroxy-4-(trifluoromethyl)-3-(phenylsulfonyl)-1,4-dihydro-2H-quinolin-2-one; 6-Chloro-3,4-dihydro-4-hydroxy-3-(phenylsulfonyl)-4-(trifluoromethyl)-2(1H)-quinolinone; 253663-82-0; 2(1H)-Quinolinone, 6-chloro-3,4-dihydro-4-hydroxy-3-(phenylsulfonyl)-4-(trifluoromethyl)-; 6-Chloro-4-hydroxy-3-(benzenesulfonyl)-4-(trifluoromethyl)-3,4-dihydroquinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 6-Chloro-3,4-Dihydro-4-Hydroxy-3-(Phenylsulfonyl)-4-(Trifluoromethyl)-2(1H)-Quinolinone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.