Description

n-Boc-α-(Phenylsulfonyl)Cyclohexylmethylamine, 97% is a high-purity, protected amine building block featuring both a tert-butoxycarbonyl (Boc) protecting group and a phenylsulfonyl moiety. This compound is essential for advanced organic synthesis, particularly in medicinal chemistry, where it serves as a versatile intermediate for constructing complex molecules with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates, especially for central nervous system (CNS) and antiviral targets.
• Peptidomimetic Research: Used to introduce constrained cyclohexylmethylamine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed in reactions utilizing the sulfonyl group as an activating or directing group for stereoselective C-C and C-N bond formation.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and protein-protein interactions due to its modifiable functional groups.
• Agrochemical Research: Acts as an intermediate in the development of new herbicides and fungicides with complex amine structures.

Basic Information

Product Name	n-Boc-α-(Phenylsulfonyl)Cyclohexylmethylamine, 97%
CAS No.	253426-70-9
Molecular Formula	C₁₈H₂₇NO₄S
Molecular Weight	353.48 g/mol
Synonyms	1-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-(phenylsulfonyl)cyclohexanemethane; tert-Butyl N-[(1-(Phenylsulfonyl)cyclohexyl)methyl]carbamate; N-Boc-1-(Phenylsulfonyl)cyclohexanemethylamine; (1-(Phenylsulfonyl)cyclohexyl)methylcarbamic acid tert-butyl ester; α-(Phenylsulfonyl)cyclohexylmethylamine N-Boc protected; Boc-Protected α-(Phenylsulfonyl)Cyclohexylmethylamine
EINECS	Contact for details

Quality Control

Our n-Boc-α-(Phenylsulfonyl)Cyclohexylmethylamine, 97% is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.