Description

5-Oxo-1-[4-(Trifluoromethyl)Benzyl]Pyrrolidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolidine carboxylic acid core and trifluoromethyl benzyl substituent. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular scaffolds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Protease Inhibitor Precursor: Serves as a core structure in the development of enzyme inhibitors due to its pyrrolidinone scaffold.
• Agrochemical Research: Used in the discovery and development of new herbicides and pesticides, leveraging the bioactivity of the trifluoromethyl group.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme function and biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique properties.

Basic Information

Product Name	5-Oxo-1-[4-(Trifluoromethyl)Benzyl]Pyrrolidine-3-Carboxylic Acid
CAS No.	253178-82-4
Molecular Formula	C13H12F3NO3
Molecular Weight	287.24 g/mol
Synonyms	1-[(4-Trifluoromethyl)benzyl]-5-oxopyrrolidine-3-carboxylic acid; 3-Carboxy-1-(4-trifluoromethylbenzyl)-2-pyrrolidinone; 5-Oxo-1-(4-trifluoromethylbenzyl)-3-pyrrolidinecarboxylic acid; 1-(4-(Trifluoromethyl)benzyl)-5-oxopyrrolidine-3-carboxylic acid; Pyrrolidine-3-carboxylic acid, 5-oxo-1-[(4-trifluoromethyl)benzyl]-; 253178-82-4; 5-Oxo-1-(4-trifluoromethyl-benzyl)-pyrrolidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Oxo-1-[4-(Trifluoromethyl)Benzyl]Pyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.