Description

[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Palladium(II) Chloride is a high-purity, chiral palladium complex widely recognized as a premier catalyst for asymmetric synthesis. Its value lies in enabling highly enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions, which are critical for producing single-isomer pharmaceutical intermediates and fine chemicals. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance catalysts for process development and scale-up.

Application

• Asymmetric Cross-Coupling Reactions: A key catalyst for enantioselective Suzuki-Miyaura, Heck, and Sonogashira couplings.
• Pharmaceutical Intermediate Synthesis: Critical for constructing chiral centers in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A staple catalyst for methodology development and exploring new asymmetric transformations in laboratory settings.
• Fine Chemical Production: Enables the commercial-scale manufacture of specialty chiral compounds for flavors, fragrances, and electronic chemicals.
• Polymer Science: Facilitates the synthesis of chiral monomers and polymers with specific optical properties.

Basic Information

Product Name	[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Palladium(II) Chloride
CAS No.	253157-79-8
Molecular Formula	C44H32Cl2P2Pd
Molecular Weight	788.00 g/mol
Synonyms	(R)-(+)-BINAP-Palladium(II) Chloride; (R)-BINAP-PdCl2; (R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl palladium dichloride; Pd(R-BINAP)Cl2; (R)-BINAP Pd(II) Chloride Complex; (R)-BINAP-PdCl2 Complex; Palladium(II) chloride (R)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl; (R)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthylpalladium(II) Chloride
EINECS	Contact for details

Quality Control

Every batch of our [(R)-(+)-BINAP-Palladium(II) Chloride is manufactured and tested under strict quality management systems to ensure exceptional purity and catalytic performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as palladium content, chiral purity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical applications, ensuring reliable and reproducible results in your most critical asymmetric syntheses.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light may degrade its catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown powder or crystals
Identification (IR)	Conforms to structure
Palladium (Pd) Content	12.0 - 14.0 %
Purity (HPLC)	≥ 97.0 %
Chiral Purity (Chiral HPLC)	≥ 99.0 % ee
Solubility	Soluble in dichloromethane, chloroform; slightly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.