Description

1H-Indole-2-Carboxylicacid,2,3-Dihydro-2-Methyl-,(2S)-(9Ci) is a chiral, non-racemic indole derivative that serves as a sophisticated building block in advanced organic synthesis. This compound is valued for its defined stereochemistry and functionalized indole core, which are critical for constructing molecules with specific biological activity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule influences efficacy.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a test substrate in the development of new chiral catalysts and synthetic methodologies.
• Biochemical Research: Utilized in studies investigating enzyme inhibition or receptor binding due to its structural similarity to natural indole alkaloids.
• Fine Chemical Production: Serves as a high-value intermediate in the multi-step synthesis of complex, specialty chemicals for various industrial applications.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,2,3-Dihydro-2-Methyl-,(2S)-(9Ci)
CAS No.	253136-56-0
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	(2S)-2,3-Dihydro-2-methyl-1H-indole-2-carboxylic acid; (S)-2-Methylindoline-2-carboxylic acid; (2S)-2-Methyl-2,3-dihydro-1H-indole-2-carboxylic acid; 2,3-Dihydro-2-methyl-1H-indole-2-carboxylic acid, (2S)-; 1H-Indole-2-carboxylic acid, 2,3-dihydro-2-methyl-, (2S)-; (S)-2-Methyl-2,3-dihydroindole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Every lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profile is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.