Description

tert-Butyl 12-Amino-4 7 10-Trioxa-Dodeca is a specialized, high-purity chemical intermediate featuring a unique polyether-amine structure. This compound matters for its role as a versatile building block in advanced organic synthesis, offering a protected amine group and a flexible, hydrophilic trioxa chain. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in creating linkers for antibody-drug conjugates (ADCs) or prodrugs.
• Polymer Modification: Used to introduce hydrophilic, flexible spacer arms into polymers, resins, and coatings to modify solubility and physical properties.
• Ligand and Chelator Synthesis: Serves as a precursor for creating polyether-based ligands and chelating agents used in catalysis and metal ion sequestration.
• Surface Functionalization: Employed to graft amine-terminated polyether chains onto surfaces for creating biocompatible or non-fouling coatings.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, or plant growth regulators requiring specific solubility profiles.
• Crosslinking Agent: Functions as a crosslinker or chain extender in the production of polyurethanes and other specialty polymers.

Basic Information

Item	Detail
Product Name	tert-Butyl 12-Amino-4 7 10-Trioxa-Dodeca
CAS No.	252881-74-6
Molecular Formula	C14H29NO4
Molecular Weight	275.39 g/mol
Synonyms	12-Amino-4,7,10-trioxadodecan-1-ol tert-butyl ether; 2-[2-[2-(2-tert-Butoxyethoxy)ethoxy]ethoxy]ethanamine; tert-Butyl tri(ethylene glycol) amine; 1-tert-Butoxy-11-amino-3,6,9-trioxaundecane; Amino-PEG3-t-butyl ether; 3,6,9-Trioxa-12-aminododecan-1-ol, 1-tert-butyl ether; tert-Butyl-PEG3-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl 12-Amino-4 7 10-Trioxa-Dodeca is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your R&D and cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.