Description

2H-1,7-Dioxacyclopent[Cd]Indene-4,5-Diol, 4,4A,5,6,7A,7B-Hexahydro-6-(Hydroxymethyl)-, (4S,4Ar,5S,6R,7As,7Bs)- (9Ci) is a complex, stereochemically defined polycyclic compound featuring fused dioxacyclopent and indene ring systems. This molecule matters as a sophisticated chiral building block or potential synthetic intermediate for advanced pharmaceutical research and fine chemical synthesis, where its specific stereochemistry and functional groups are critical. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients or complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) or anti-infective therapeutics.
• Asymmetric Catalysis Ligand Precursor: Its rigid, oxygen-rich structure can be modified to develop novel ligands for asymmetric synthesis.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to construct complex, polycyclic natural product analogs or specialty materials.
• Agrochemical Research: Acts as an advanced intermediate for developing new generation pesticides or herbicides with specific stereochemical requirements.
• Academic & Institutional Research: Employed in methodological studies and the exploration of new chemical reactions involving fused oxygen heterocycles.
• Material Science Exploration: Potential monomer or precursor for synthesizing specialized polymers with unique thermal or optical properties.

Basic Information

Product Name	2H-1,7-Dioxacyclopent[Cd]Indene-4,5-Diol, 4,4A,5,6,7A,7B-Hexahydro-6-(Hydroxymethyl)-, (4S,4Ar,5S,6R,7As,7Bs)- (9Ci)
CAS No.	251914-66-6
Molecular Formula	C12H16O5
Molecular Weight	240.25 g/mol
Synonyms	(4S,4aR,5S,6R,7aS,7bS)-4,4a,5,6,7a,7b-Hexahydro-6-(hydroxymethyl)-2H-1,7-dioxacyclopent[cd]indene-4,5-diol; Hexahydro-6-(hydroxymethyl)-2H-1,7-dioxacyclopent[cd]indene-4,5-diol (stereoisomer); CAS 251914-66-6; Polycyclic dioxacyclopentindene diol derivative; Chiral fused tetrahydropyran-dihydrofuran intermediate.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and chiral purity. For advanced intermediates like this, quality is assured through techniques including HPLC, chiral HPLC, NMR, and mass spectrometry to confirm structural integrity and stereochemical purity. Specifications can be developed to meet cGMP or other stringent regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and purity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.