Description

Bromobis(Ph3P)(n-Succinimide)Pd(II) is a specialized palladium(II) complex catalyst, widely recognized for its high activity and selectivity in cross-coupling reactions. This compound matters for its crucial role in facilitating efficient carbon-carbon and carbon-heteroatom bond formation, which are fundamental steps in modern synthetic organic chemistry. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing active pharmaceutical ingredients (APIs), novel crop protection agents, and functional organic molecules.

Application

• Suzuki-Miyaura Cross-Coupling: A key catalyst for coupling aryl/vinyl boronic acids with aryl/vinyl halides, essential for constructing biaryl structures in drug discovery.
• Buchwald-Hartwig Amination: Facilitates the coupling of amines with aryl halides for the synthesis of aryl amines, a common motif in pharmaceuticals and materials.
• Heck Reaction (Mizoroki-Heck): Enables the coupling of alkenes with aryl/vinyl halides for the synthesis of substituted alkenes.
• Precursor for Active Catalytic Species: Serves as a well-defined, air-stable precursor to generate highly active, low-ligand Pd(0) species in situ.
• Fine Chemical and API Synthesis: Used in the scalable, process-friendly synthesis of complex organic intermediates and final active pharmaceutical ingredients.
• Polymer and Material Science: Applied in the synthesis of conjugated polymers and organic electronic materials via controlled cross-coupling polymerization.

Basic Information

Product Name	Bromobis(Ph3P)(n-Succinimide)Pd(II)
CAS No.	251567-28-9
Molecular Formula	C40H34BrN1O2P2Pd1
Molecular Weight	818.97 g/mol
Synonyms	Bromobis(triphenylphosphine)(N-succinimidato)palladium(II); Palladium, bromobis(triphenylphosphine)(2,5-dioxo-1-pyrrolidinyl-κN)-; Bromo(N-succinimidato)bis(triphenylphosphine)palladium(II); Bromo(2,5-dioxopyrrolidin-1-ato-κN)bis(triphenylphosphine)palladium(II); (N-Succinimidato)bromobis(triphenylphosphine)palladium(II); Pd(PPh3)2Br(NSI); Bromobis(triphenylphosphine)(N-succinimido)palladium
EINECS	Contact for details

Quality Control

Our Bromobis(Ph3P)(n-Succinimide)Pd(II) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and ICP-MS for heavy metal content, to meet the stringent requirements of process chemistry and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent decomposition. The material is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (Pd content)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Heavy Metals (ICP-MS)	< 20 ppm
Solubility	Soluble in common organic solvents (DCM, THF, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.