Description

2-Propanone, 1-(Ethylsulfinyl)-, (+)- (9Ci) is a chiral sulfoxide derivative of acetone, a valuable building block in asymmetric synthesis. Its unique structure makes it a versatile chiral auxiliary and ligand precursor for catalytic reactions, offering significant value in the production of enantiomerically pure compounds. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Catalyst & Ligand Precursor: Used in the development and preparation of chiral catalysts and ligands for transition metal-catalyzed reactions, such as asymmetric oxidations and C-H activations.
• Fine Chemical Synthesis: Employed in research-scale and pilot-scale organic synthesis to introduce the chiral ethylsulfinyl moiety into complex molecules for agrochemicals and advanced materials.
• Asymmetric Methodology Development: A critical reagent in academic and industrial R&D for exploring new asymmetric synthetic routes and studying stereochemical outcomes.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in chiral separation techniques like HPLC and SFC.

Basic Information

Product Name	2-Propanone, 1-(Ethylsulfinyl)-, (+)- (9Ci)
CAS No.	251565-64-7
Molecular Formula	C5H10O2S
Molecular Weight	134.20 g/mol
Synonyms	(+)-1-(Ethylsulfinyl)acetone; (R)-1-(Ethylsulfinyl)acetone; (+)-1-(Ethylsulfinyl)-2-propanone; 1-Acetone, 1-(ethylsulfinyl)-, (+)-; (R)-1-(Ethylsulfinyl)propan-2-one; (R)-1-(Ethylsulfinyl)acetone; (R)-1-(Ethylsulfinyl)propan-2-one; 1-(Ethylsulfinyl)acetone, (+)-
EINECS	Contact for details

Quality Control

Our production of 2-Propanone, 1-(Ethylsulfinyl)-, (+)- adheres to stringent quality protocols suitable for research and pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.