Description

8-(1-Naphthalenylmethyl)-4-Oxo-1-Phenyl-1,3,8-Triazaspiro[4.5]Decane-3-Acetic Acid, Methyl Ester is a high-purity, complex organic compound featuring a spirocyclic triaza structure, which is of significant interest in advanced synthetic chemistry. This compound serves as a critical building block or key intermediate in the research and development of novel pharmaceutical agents, particularly those targeting central nervous system disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of potential drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe: Serves as a tool compound for investigating biological pathways and protein-ligand interactions in academic and industrial research settings.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) during pre-clinical and clinical development phases.
• Reference Standard: Used as an analytical standard for quality control and method validation in laboratories manufacturing or researching related compounds.
• Custom Synthesis: A starting material for the contract synthesis of specialized, non-commercially available derivatives for client-specific research projects.

Basic Information

Item	Detail
Product Name	8-(1-Naphthalenylmethyl)-4-Oxo-1-Phenyl-1,3,8-Triazaspiro[4.5]Decane-3-Acetic Acid, Methyl Ester
CAS No.	250685-44-0
Molecular Formula	C27H29N3O3
Molecular Weight	443.54 g/mol
Synonyms	Methyl 8-(naphthalen-1-ylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-3-acetate; 1,3,8-Triazaspiro[4.5]decane-3-acetic acid, 8-(1-naphthalenylmethyl)-4-oxo-1-phenyl-, methyl ester; 250685-44-0; Methyl 8-(1-naphthylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-3-acetate; Spirotriaza derivative; 8-(1-Naphthylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-3-acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 8-(1-Naphthalenylmethyl)-4-Oxo-1-Phenyl-1,3,8-Triazaspiro[4.5]Decane-3-Acetic Acid, Methyl Ester adheres to stringent quality protocols suitable for research and development applications. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (IR, NMR), and impurity profiles are provided and available upon request. We support cGMP-compliant manufacturing for advanced development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.