Description

4-Chloro-[1,7]Naphthyridine-2-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable heterocyclic building block. This compound is essential for pharmaceutical research and development, serving as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways where the naphthyridine scaffold is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for creating advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research due to its modifiable functional groups.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and novel synthetic route exploration.
• Fine Chemical Synthesis: Acts as a specialized intermediate for custom synthesis and the production of high-value, low-volume specialty chemicals.

Basic Information

Product Name	4-Chloro-[1,7]Naphthyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	250674-51-2
Molecular Formula	C11H9ClN2O2
Molecular Weight	236.66 g/mol
Synonyms	Ethyl 4-Chloro-1,7-naphthyridine-2-carboxylate; 4-Chloro-1,7-naphthyridine-2-carboxylic acid ethyl ester; 2-Carbethoxy-4-chloro-1,7-naphthyridine; 4-Chloro-1,7-naphthyridine-2-carboxylic acid, ethyl ester; 250674-51-2; Ethyl 4-chloro[1,7]naphthyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Chloro-[1,7]Naphthyridine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.