Description

(S)-α-Amino-1,3-benzodioxole-5-acetic acid is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. Its value lies in its role as a key building block for the production of active pharmaceutical ingredients (APIs) and other fine chemicals requiring specific stereochemistry. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and biotechnology sectors seeking reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production route of APIs that require the (S)-enantiomer of this benzodioxole acetic acid derivative.
• Asymmetric Synthesis: Serves as a starting material or intermediate in asymmetric catalytic processes to introduce chirality into target molecules.
• Agrochemical Research: Employed in the development of new, enantiomerically pure pesticides and herbicides.
• Bioconjugation & Peptidomimetics: Useful in the design and synthesis of peptide analogs and bioconjugates due to its amino and carboxylic acid functional groups.
• Chemical Biology Probes: Acts as a precursor for labeled compounds used in biochemical and pharmacological studies.

Basic Information

Item	Detail
Product Name	(S)-α-Amino-1,3-benzodioxole-5-acetic Acid
CAS No.	250666-02-5
Molecular Formula	C10H9NO5
Molecular Weight	223.18 g/mol
Synonyms	(S)-2-Amino-2-(1,3-benzodioxol-5-yl)acetic acid; (S)-α-Amino-1,3-benzodioxole-5-acetic acid; (S)-Amino-benzodioxole-acetic acid; (S)-2-(Benzo[d][1,3]dioxol-5-yl)glycine; (S)-5-Carboxymethyl-1,3-benzodioxole amine; (S)-BDA; (S)-2-Amino-2-(3,4-methylenedioxyphenyl)acetic acid
EINECS	Contact for details

Quality Control

Our (S)-α-Amino-1,3-benzodioxole-5-acetic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.