Description

8-Fluoroquinoline-2,4-Dicarboxylic Acid is a high-purity fluorinated quinoline derivative, serving as a critical multifunctional building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and two carboxylic acid groups, which allow for precise structural modifications to develop novel compounds with targeted properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotics and other bioactive molecules targeting bacterial infections.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand Synthesis: Serves as a versatile scaffold for creating complex chelating ligands used in catalysis and material science.
• Fluorescent Probe Development: The quinoline core is utilized in constructing advanced fluorescent dyes and molecular probes for diagnostic and imaging applications.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for synthesizing specialty polymers with unique thermal or optical properties.
• Academic & R&D: A valuable compound for medicinal chemistry research, structure-activity relationship (SAR) studies, and exploring new chemical entities.

Basic Information

Product Name	8-Fluoroquinoline-2,4-Dicarboxylic Acid
CAS No.	250641-22-6
Molecular Formula	C₁₁H₆FNO₄
Molecular Weight	235.17 g/mol
Synonyms	2,4-Quinolinedicarboxylic acid, 8-fluoro-; 8-Fluoro-2,4-quinolinedicarboxylic acid; 8-Fluoroquinoline-2,4-dicarboxylic acid; 250641-22-6; 8-Fluoro-2,4-dicarboxyquinoline; 8-Fluoro-2,4-pyridinedicarboxylic acid (related); 8-Fluoroquinoline dicarboxylic acid; 8-FQDA
EINECS	Contact for details

Quality Control

Our 8-Fluoroquinoline-2,4-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which could affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.