Description

Di-Fmoc-3,5-Diaminobenzoic Acid is a high-purity, bifunctional protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical key building block in the construction of complex molecules, particularly in peptide and combinatorial chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for developing novel active compounds and materials.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected diamine derivative, it is used to incorporate a 3,5-diaminobenzoic acid scaffold into peptide chains, enabling the creation of branched or dendrimeric peptide structures.
• Combinatorial Library Synthesis: Serves as a versatile core scaffold for generating diverse libraries of small molecules and peptidomimetics for high-throughput screening in drug discovery.
• Linker Molecule for Bioconjugation: The dual Fmoc-protected amine groups and carboxylic acid functionality allow for controlled, sequential conjugation to other molecules, proteins, or solid supports.
• Synthesis of Dendrimers and Polymers: Acts as a trifunctional monomer for constructing dendrimers and specialty polymers with precise architectures for material science applications.
• Intermediate for Fluorescent Probes and Dyes: The aromatic diaminobenzoic acid core is a precursor for synthesizing advanced organic fluorophores and imaging agents.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) that require a functionalized aromatic diamine component.

Basic Information

Item	Details
Product Name	Di-Fmoc-3,5-Diaminobenzoic Acid
CAS No.	248602-44-0
Molecular Formula	C39H32N2O6
Molecular Weight	624.69 g/mol
Synonyms	3,5-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]amino]benzoic Acid; 3,5-Bis(Fmoc-amino)benzoic Acid; 3,5-Di-Fmoc-aminobenzoic Acid; 3,5-Bis[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]benzoic Acid; N3,N5-Bis(9-fluorenylmethoxycarbonyl)-3,5-diaminobenzoic Acid; Di-Fmoc-DABA; 3,5-Diaminobenzoic Acid Di-Fmoc Derivative; 3,5-Bis(Fmoc-NH)-Bz-OH
EINECS	Contact for details

Quality Control

Our Di-Fmoc-3,5-Diaminobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and identity, typically meeting standards suitable for research and pharmaceutical development. Certificates of Analysis (COA) detailing purity (HPLC), identity (IR, NMR), and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.