Description

2H-Thiopyran-2-Carboxylicacid,3,6-Dihydro-,1-Oxide,(1R,2S)-Rel-(+)-(9Ci) is a high-purity, stereochemically defined chiral building block with the CAS number 247934-09-4. This compound is valued for its unique thiopyran oxide scaffold, which serves as a versatile intermediate in the synthesis of complex, biologically active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas requiring specific stereochemistry.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for creating libraries of novel compounds.
• Asymmetric Synthesis: Serves as a building block in catalytic and stoichiometric asymmetric reactions to construct complex molecular architectures.
• Agrochemical Research: Employed in the synthesis of novel pesticides and herbicides where the thiopyran moiety can confer specific biological activity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting advanced organic synthesis projects.

Basic Information

Product Name	2H-Thiopyran-2-Carboxylicacid,3,6-Dihydro-,1-Oxide,(1R,2S)-Rel-(+)-(9Ci)
CAS No.	247934-09-4
Molecular Formula	C6H8O3S
Molecular Weight	160.19 g/mol
Synonyms	(1R,2S)-rel-3,6-Dihydro-2H-thiopyran-2-carboxylic acid 1-oxide; (+)-rel-(1R,2S)-3,6-Dihydro-2H-thiopyran-2-carboxylic acid 1-oxide; 2H-Thiopyran-2-carboxylic acid, 3,6-dihydro-, 1-oxide, (1R,2S)-rel-; Thiopyran-2-carboxylic acid, 3,6-dihydro-, 1-oxide, (1R,2S)-rel-; Chiral thiopyran oxide carboxylic acid; 247934-09-4; (1R,2S)-rel-3,4-Dihydro-2H-thiopyran-2-carboxylic acid 1-oxide (alternative numbering).
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 2H-Thiopyran-2-Carboxylicacid,3,6-Dihydro-,1-Oxide,(1R,2S)-Rel-(+)-(9Ci) is characterized and tested to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specifications such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and residual solvent content are available upon request. We adhere to cGMP principles where applicable to support our clients' advanced research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.