Description

(1S,2S)-(-)-n-(2,4,6-Trimethylphenylsulfonyl)-1,2-Diphenylethane-1,2-Diamine is a high-purity, chiral diamine derivative featuring a mesitylsulfonyl protecting group. This compound is a critical chiral ligand and building block in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and manufacturing in the pharmaceutical, agrochemical, and advanced materials sectors where precise stereochemical control is paramount.

Application

• Asymmetric Catalysis: Serves as a key chiral ligand or precursor for transition metal catalysts used in enantioselective hydrogenation, alkylation, and other C-C bond-forming reactions.
• Pharmaceutical Intermediates: A vital building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific (1S,2S) stereochemistry.
• Chiral Auxiliary: Used to induce chirality in synthetic pathways for complex organic molecules in fine chemical production.
• Agrochemical Synthesis: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry laboratories.
• Material Science: Potential monomer or modifier for creating chiral polymers and advanced functional materials.

Basic Information

Item	Details
Product Name	(1S,2S)-(-)-n-(2,4,6-Trimethylphenylsulfonyl)-1,2-Diphenylethane-1,2-Diamine
CAS No.	247923-40-6
Molecular Formula	C29H30N2O2S
Molecular Weight	470.63 g/mol
Synonyms	(1S,2S)-(-)-1,2-Diphenyl-N-(2,4,6-trimethylphenylsulfonyl)ethane-1,2-diamine; (1S,2S)-TsDPEN (Mesityl); (1S,2S)-(-)-N-(Mesitylsulfonyl)-1,2-diphenylethylenediamine; (1S,2S)-N-(2,4,6-Trimethylbenzenesulfonyl)-1,2-diphenylethylenediamine; (1S,2S)-MsDPEN; (1S,2S)-(-)-N-Mesityl-1,2-diphenylethylenediamine; (1S,2S)-DPEN-Mesyl; (1S,2S)-1,2-Diamino-1,2-diphenylethane N-mesitylenesulfonamide
EINECS	Contact for details

Quality Control

Our (1S,2S)-(-)-n-(2,4,6-Trimethylphenylsulfonyl)-1,2-Diphenylethane-1,2-Diamine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for asymmetric synthesis and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.