Description

Hydroxylamine, o-[(1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl]- (9Ci) is a specialized chiral hydroxylamine derivative with a complex, sterically hindered structure based on a menthol-like scaffold. This compound matters as a high-value, stereochemically defined building block for the synthesis of advanced pharmaceuticals and fine chemicals, where precise spatial orientation is critical for biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or with complex stereochemical requirements.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides and herbicides where specific isomer activity is desired for efficacy and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Fine Chemical Synthesis: Employed in the multistep synthesis of complex natural products, flavors, and fragrances that require the introduction of a protected hydroxylamine or amine functionality with defined stereochemistry.
• Material Science Research: Potential building block for creating chiral polymers or surfaces with specific interactive properties for separation science or sensor technology.

Basic Information

Product Name	Hydroxylamine, o-[(1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl]- (9Ci)
CAS No.	247142-89-8
Molecular Formula	C10H21NO
Molecular Weight	171.28 g/mol
Synonyms	(1R,2S,5R)-Menthyloxyamine; o-((1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl)hydroxylamine; (-)-Menthyloxyamine; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyloxyamine; L-Menthyl O-hydroxylamine; (1R,2S,5R)-Menthyl O-hydroxylamine
EINECS	Contact for details

Quality Control

Every batch of Hydroxylamine, o-[(1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl]- (9Ci) is produced and controlled under a strict quality management system. We employ advanced analytical techniques, including chiral HPLC, NMR, and GC-MS, to ensure high enantiomeric purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, well-ventilated place. Due to its sensitivity to oxidation, the container should be kept sealed and only opened in a controlled environment. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.